Pulmonary Hypertension News – Pulmonary Hypertension News
Jan 13, 2025 · Winrevair regimen balances efficacy, safety in PAH: Analysis. The dosing regimen for Winrevair (sotatercept-csrk) is optimal for balancing efficacy and safety in adults with pulmonary arterial hypertension (PAH), an analysis of clinical trial data shows.
Pulmonary Arterial Pressure Above 30 mmHg Linked to Increased...
Jul 8, 2019 · An estimated right ventricular systolic pressure (eRVSP) — a measure of the pressure inside the artery that supplies blood to the lungs (pulmonary artery) — greater than 30.0 mmHg is related to an increased risk of mortality in patients with pulmonary hypertension (PH), according to a new Australian study.
Winrevair regimen balances efficacy, safety in PAH: Analysis
Jan 17, 2025 · The dosing regimen for Winrevair (sotatercept-csrk) is optimal for balancing efficacy and safety in adults with pulmonary arterial hypertension (PAH), an analysis of clinical trial data shows. This regimen is “well-justified based on the totality of the observed safety and efficacy data from Phase ...
Adempas helps lower risk in PAH patients, newer risk model …
4 days ago · People with pulmonary arterial hypertension (PAH) seen to be at an intermediate risk of death — whether in the low or high range of that middle-level risk — were more likely to have better outcomes when treated with Adempas (riociguat) than given a placebo in a Phase 3 clinical trial, its data show.
Including Uptravi early in PAH treatment lowers hospitalization risk
Nov 8, 2024 · The study, “ Early Addition of Selexipag to Double Therapy for Pulmonary Arterial Hypertension,” was published in JAMA Network Open.The work was funded by Actelion Pharmaceuticals, a part of Johnson & Johnson, which sells Uptravi.. PAH is marked by increased blood pressure in the vessels of the lungs, which puts strain on the heart.
PAH symptom discordance with patients, physicians tied to worse...
Dec 20, 2024 · In PAH, high blood pressure in the blood vessels that carry blood from the heart to the lungs results in symptoms like shortness of breath, fatigue, and chest pain. The disease can make even simple activities, like walking or climbing stairs, increasingly difficult and negatively impacts patients’ quality of life.
Incidence of PAH Is 5.8 New Cases Per Million People, Review Finds
Jan 27, 2021 · In adults with PAH, the incidence varied from 1.5 to 32 patients per million (ppm) and prevalence from 12.4 to 268 ppm. Similarly, in adults with CTEPH, the ranges of incidence were from 0.9 to 39 ppm and prevalence from 14.5 to 144 ppm.
Pulmonary Hypertensive Crisis
Pulmonary hypertensive crises are moments of stress during which the pulmonary pressure increases drastically, resulting in an overload of pressure on the right heart ventricle and drop in cardiac output.. Due to these episodes, patients are at higher risk of suffering hypoxia, which is consistent with poor levels of oxygen in the tissues and can cause an even more severe increase in pulmonary ...
Pulmonary hypertension death rate falling, but not all across globe
Mar 6, 2024 · While all types of PH are linked to an increased risk of death, there are limited data on mortality trends around the world. To get a broader picture of PH-related mortality trends, the researchers drew on World Health Organization data. Between 2000 and 2019, PH accounted for 491,287 deaths across the 54 countries included in the report.
The management of pulmonary hypertension is a long road
Aug 18, 2023 · A typical visit goes as follows: Check in, take vital signs, conduct a six-minute walk test (while subconsciously trying to beat the numbers for a previous effort), and undergo an echocardiogram, a chest X-ray, and various labs.The results vary but rarely improve significantly, which would be a dream come true for a PAH patient.