The sinoatrial node (also known as the sinuatrial node, SA node or sinus node) is an oval shaped region of special cardiac muscle in the upper back wall of the right atrium made up of cells known as pacemaker cells.

An electrical stimulus is generated by the sinus node (also called the sinoatrial node, or SA node). This is a small mass of specialized tissue located in the right upper chamber (atria) of the heart.

Oct 30, 2023 · The sinoatrial node, better known as the sinuatrial or SA node is the key structure responsible for the generation of a regular heartbeat and is therefore often referred to as the pacemaker of the heart.

Oct 3, 2022 · The SA node, or the sinus node, represents a crescent-like cluster of myocytes divided by connective tissue, spreading over a few square millimeters. It is located at the junction of the crista terminalis in the upper wall of the right atrium and the opening of …

Apr 24, 2023 · The sinoatrial (SA) node is a collection of specialised cells (pacemaker cells), and is located in the upper wall of the right atrium, at the junction where the superior vena cava enters. These pacemaker cells can spontaneously generate electrical impulses.

Jan 17, 2025 · Your sinoatrial (SA) node is your heart’s natural pacemaker. It sends the electrical impulses that start your heartbeat. When your sinoatrial node isn’t working well, the lower segments of your conduction system act as backup pacemaker cells.

Jul 18, 2019 · The sinoatrial node, also referred to as the pacemaker of the heart, coordinates heart contractions. Located in the upper wall of the right atrium , it generates nerve impulses that travel throughout the heart wall causing both atria to contract.

Spontaneous action potentials generated by the pacemaker cells of the sinoatrial node (SA) node are the first step in the chain of events that comprise each cardiac cycle.

The Sinoatrial Node is a specialized cluster of muscle fibers located in the right atrium of the heart, responsible for generating electrical impulses that regulate the heart's rhythm. You might find these chapters and articles relevant to this topic. Andrew J. Connolly MD, PhD, ... Richard L. Davis MD. Sinoatrial Node.

In the upper part of the right atrium of the heart is a specialized bundle of neurons known as the sinoatrial node (SA node). Acting as the heart's natural pacemaker, the SA node "fires" at regular intervals to cause the heart of beat with a rhythmn of about 60 to 70 beats per minute for a healthy, resting heart.

Cells within the sinoatrial (SA) node are the primary pacemaker site within the heart. These cells are characterized as having no true resting potential, but instead generate regular, spontaneous action potentials.

The sinoatrial node (SAN) automaticity is essential for maintaining normal cardiac function. Sick sinus syndrome is an abnormality involving the generation of the action potential by the SAN and is characterized by an atrial rate inappropriate for physiological requirements.

Dec 13, 2020 · The sinoatrial node, often referred to as the SA node, is the pacemaker of the heart. It is located in the right atrium and is responsible for generating normal sinus rhythm. The sinoatrial node is located lateral to the junction where …

In the adult human, the node is approximately 1 mm below the epicardium, 10-20 mm long, and up to 5 mm thick [1,16]. Figure 1. The conduction system of the heart. Normal excitation originates in the sinoatrial (SA) node, then propagates through both …

The sinoatrial node (SAN) is the primary pacemaker of the heart and responsible for initiating and regulating cardiac rhythm 1-9. SAN automaticity and conduction depends on the unique heterogeneous distribution of intracellular ion channels, Ca 2+ handling proteins and autonomic receptors within the SAN 10 - 12 as well as the unique structure ...

Jul 22, 2023 · Explore the physiology of the sinoatrial (SA) node, the natural pacemaker of the heart. Learn about its structure, electrical activity, significance in heart function, and clinical implications in heart rhythm disorders.

Sep 13, 2022 · It is a single, elongated, 3-dimensional (3D) intramural fibrotic structure located at the junction of the superior vena cava intercaval region bordering the crista terminalis (CT). SAN activation originates in the intranodal pacemakers and is conducted to the atria through 1 or more discrete sinoatrial conduction pathways.

The sinuatrial node (also commonly spelled sinoatrial node, abbreviated SA node or SAN, also called the sinus node) is the impulse-generating tissue located in the right atrium of the heart, and thus the generator of normal sinus rhythm.

Oct 3, 2022 · Martin Flack, a medical student, was the first to discover the sinoatrial (SA) node in the early 1900s. The SA node represents a cluster of myocytes with pacemaker activity. Under normal circumstances, it generates electrical impulses that set the rhythm and rate of the heart.

The sinoatrial node (SAN) is the primary pacemaker of the human heart. It is a single, elongated three-dimensional (3D) intramural fibrotic structure located at the junction of the superior vena cava intercaval region bordering the crista terminalis (CT).