Bacteriophage P2, scientific name Peduovirus P2 (formerly Escherichia virus P2), [1] is a temperate phage that infects E. coli. It is a tailed virus with a contractile sheath and is thus classified in the genus Peduovirus (formerly P2likevirus), family …

Mar 16, 2016 · P2 is the original member of a highly successful family of temperate phages that are frequently found in the genomes of gram-negative bacteria. This article focuses on the organization of the P2 genome and reviews current knowledge about the …

We identified 9371 tailed phage prophages of 20 known types in reported complete genome sequences of 3298 bacteria in the Salmonella genus. These include 4758 P2 type and 744 P22 type prophages.

Our study provides the first evidence that engineering the P2 tail fiber can extend the host range toward novel proteinaceous receptors, thus opening new potential applications for “designer bacteriophage” based on phage P2 in biotechnology fields.

Bacteriophage P4 is a satellite phage that relies on the P2-related helper phage for lytic replication. (20) The P4 δ activates P2 late genes, (21) while ε activates lytic replication of P2 prophage.

Bacteriophage P2 belongs to a group of bacteriophages found in E. coli and other hosts referred to as the P2-like bacteriophages, that also includes phage 186 [29] and Salmonella phage SopEϕ [30]. These phages share a common genomic organization and all encode a gpO-like protein [10] .

Here, we discovered a P2-family prophage integrated at the 3'-end of ssrA in the deep-sea bacterium S. putrefaciens. We found that ~0.1% of host cells are lysed to release P2 constitutively during host growth.

By this process, a P2 phage infecting a P4 lysogen is capable of inducing replication of the P4 genome, an example of viral transactivation. In this report, we present evidence that Cox is also directly involved in both prophage excision and phage integration.

P2 is the original member of a highly successful family of temperate phages that are frequently found in the genomes of gram-negative bacteria. This article focuses on the organization of the P2 genome and reviews current knowledge about the function of each open reading frame.

Oct 21, 2022 · Here, we re-engineered the Escherichia coli phage P2 to alter its tropism toward pathogenic bacteria. Chimeric tail fibers formed between P2 and S16 genes were designed and generated through two approaches: homology- and literature-based.