Jan 24, 2022 · Ovarian cancer tumor markers can help assess the effectiveness of treatment and check for disease progression. Learn about the different types of tests.

Tumor markers, particularly CA-125, are widely used in the diagnosis of ovarian cancer but have limitations in sensitivity and specificity, especially in early-stage and certain subtypes of the disease.

Many women with ovarian cancer have high levels of CA-125. This test can be useful as a tumor marker to help guide treatment in women known to have ovarian cancer, because a high level often goes down if treatment is working. But checking CA-125 levels has not been found to be as useful as a screening test for ovarian cancer.

May 31, 2022 · Ovarian cancer tumor markers are chemical compounds that cancer cells produce. Doctors can use different types to help diagnose ovarian cancer.

Not everyone with ovarian cancer will have a high tumor marker level. Some of the biomarkers are: CA-125 (Cancer antigen 125) The ovarian cancer tumor marker test that is most often used. It helps diagnose, see how well treatment is working, and check if the cancer has returned after treatment. HE4 (Human epididymis protein 4) More sensitive ...

Most ovarian cancers are diagnosed at advanced stages (Stage III or IV). This means that at the time of diagnosis, the cancer has already spread beyond the female organs into the upper abdomen, lymph nodes or the chest.

Feb 20, 2024 · CA 125: CA 125 is a tumor marker that is primarily associated with ovarian cancer. Elevated levels of CA 125 may indicate the presence of ovarian cancer, but it can also be elevated in other conditions such as endometriosis and pelvic inflammatory disease. 2. PSA: PSA (prostate-specific antigen) is a tumor marker used for prostate cancer.

Jun 1, 2016 · Women who have symptoms concerning for ovarian cancer should undergo a physical examination, transvaginal ultrasonography, and measurement of biomarkers such as cancer antigen 125. If results...

Aug 5, 2023 · Results: HE4, when combined with CA-125, shows improved sensitivity and specificity, particularly in early-stage detection. Additionally, hCG holds promise as a prognostic marker, aiding treatment response prediction and outcome assessment.

Aug 5, 2023 · Ovarian cancer (OC) is characterized by silent progression and late-stage diagnosis. It is critical to detect and accurately diagnose the disease early to improve survival rates.