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  1. Management of breakthrough pain due to cancer - PMC

    Breakthrough pain is defined as the transient exacerbation of pain occurring in a patient with otherwise stable, persistent pain. It is estimated to affect over 50% of patients, particularly …

  2. Guidelines for the Management of Breakthrough Pain in Patients With Cancer

    Breakthrough pain has been defined in recent guidelines as “transitory exacerbations of pain that occur on a background of stable pain otherwise adequately controlled by around-the-clock …

  3. Breakthrough cancer pain – still a challenge - PMC

    Nov 19, 2012 · Breakthrough cancer pain is defined as transient pain exacerbation in patients with stable and controlled basal pain. Although variable, the prevalence of breakthrough cancer …

  4. Breakthrough Pain in Cancer Patients— Characteristics, Impact, …

    Jun 3, 2011 · A structured and appropriate approach to the assessment and diagnosis of breakthrough pain needs to be comprehensive to identify all the areas of impact on a patient’s …

  5. Breakthrough pain is transitory pain that occurs despite the use of opioids for background pain control. Breakthrough pain occurs in 40% to 80% of patients with cancer pain. Despite …

  6. Breakthrough Pain in Patients with Cancer: Essential Concepts …

    Nov 19, 2009 · Describe the pathophysiology and characteristics of breakthrough pain, its prevalence, and the negative impact on patients. Explain the pharmacokinetics of opioids, …

  7. Breakthrough Pain in Cancer Patients - Clinical Oncology

    Breakthrough pain is a transient exacerbation of pain that occurs either spontaneously or in relation to a specific predictable or unpredictable trigger, despite relatively stable and …

  8. Management of breakthrough pain in patients with cancer

    This article outlines a systematic, clinical and evidence-based approach to managing BTP in patients with cancer that emphasizes a holistic approach and an understanding of …

  9. Assessment and treatment of breakthrough cancer pain: from …

    Breakthrough cancer pain (BTcP) is a common condition in oncological patients. However, its management is still suboptimal. Improved knowledge of BTcP and its management in clinical …

  10. Recently developed guidelines support this approach and recommend treating breakthrough pain using rapid- or short-acting opioids with pharmacodynamics that mirror the rapid onset and …