Researchers developed SNIPRs, innovative receptors that sense soluble ligands, enabling precise therapeutic control in CAR ...

Most cell signals are chemical in nature. For example, prokaryotic organisms have sensors that detect nutrients and help them navigate toward food sources. In multicellular organisms, growth ...

Signal transduction by cell adhesion receptors and the ... Parsons, J. T. et al. Focal adhesion kinase: Targeting adhesion signaling pathways for therapeutic intervention. Clinical Cancer Research ...

Label-free biosensor assay detects Toll-like receptor signals and even discriminates between different signaling pathways.

Ludwig Cancer Research scientists have devised new types of chimeric antigen-receptor (CAR ... on a cancer cell, its signaling modules are activated and trigger the T cell's innate cytotoxic ...

Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, ...

University of Bonn researchers developed a new technique to study immune cell receptors ... for example, when the receptor ...

Our additional preliminary studies demonstrate that dual targeting of multiple myeloma cells and BM-CAFs by CAR-T cells is ...

Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...

leptin signaling intersects with insulin pathways in pancreatic β-cells. When leptin binds to its receptors in these cells, ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science ...