Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...
Rett syndrome is a severe neurodevelopmental disorder in girls, underpinned by mutations in the X-linked gene MECP2. In their ...
A NOTCH1-SOX2 negative feedback mechanism was linked with resistance to GSI. SOX2-induced inhibition of Notch signaling in ...
Hypoglycemia is an extremely common side effect of insulin therapy experienced mainly by patients with type 1 diabetes ...
A new resource by Rappe et al (2024) now provides a spatiotemporal landscape of mitophagy changes during mouse brain aging at ...
Increased H3K27ac levels upon tumor infiltration enhance Sp1-mediated expression of the GPR160 in dorsal root ganglia, which ...
Environmental pollution is a major health problem that affects the health of individuals worldwide and is cumulative with ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The impact of negative selection against ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The first step of successful infection by any ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Sepsis is a heterogeneous syndrome resulting ...