In addition to having broader clinical utility, zoledronic acid can safely be infused over 15 minutes rather than the 2 hours recommended for pamidronate. The infusion protocol for zoledronic acid ...

Orwoll, E. et al. Efficacy and safety of a once-yearly i.v. infusion of zoledronic acid 5 mg versus a once-weekly 70 mg oral alendronate in the treatment of male osteoporosis: a randomized ...

Patients received methotrexate 7.5–20 mg per week, plus either zoledronic acid 5 mg infusion (n = 18) or placebo (n = 21), at baseline and in week 13. MRI and radiographic assessments of hand ...

In the comparative phase 3 trial of zoledronic acid and pamidronate in patients ... primarily after the first and second infusions. However, these adverse events are transient and manageable ...