Evidence has emerged about the way bacteria become resistant to multiple drugs. The findings by a John Innes Centre research ...

Targeting of bacterial gyrase, specifically the gyrB subunit, is a promising approach because of this enzyme's essential role in bacterial DNA replication and its absence in higher eukaryotes.

Nature Research Intelligence Topics enable transformational understanding and discovery in research by categorising any document into meaningful, accessible topics. Read this blog to understand ...

In partnership with Jagiellonian University (Poland), and the John Innes Centre, our researchers outlined how a bacterial enzyme called DNA gyrase twists and stabilises DNA. Found in all bacteria but ...

In this example, the targets of ciprofloxacin are the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV (not shown). Figure 6. Scheme of putative synergism between a cationic α-helix AMP with ...

When the Hamilton County Coroner reopens the case decades later, new DNA technology begins identifying more victims.

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...

At NC State University, an English professor is searching for clues from the past. He's looked back as far as the eighth ...

A new study claims to have identified the first speakers of Indo-European language, which gave rise to English, Sanskrit and ...

Stanford Medicine researchers sifted through thousands of single nucleotide mutations in DNA to identify fewer than 400 that are functionally associated with inherited cancer risk.