Patients with AAV who received avacopan vs standard glucocorticoid-based regimens had lower exposure-adjusted rates of AEs, infections, and neutropenia/lymphopenia.

aDepartments of Surgery, New York University, New York, NY, USA bDepartment of Medicine, New York University, New York, NY, USA ...

When I chose vasculitis as a subject for this space, little did I know that it is the overall term for roughly twenty relatively rare, autoimmune diseases. Hang on while I try to explain what it is, ...

1 These autoantibodies activate myeloid cells (neutrophils and monocytes) and thus induce small vessel vasculitis, resulting in inflammation and damage of the kidney, lung, skin and other organs.

Further, Th17 and IL-17 may play an important role in IgAV, BD, and kidney injury in AAV. The uniqueness of each vasculitis type may differ from specific gut microbiota changes and differences in ...

Early detection and new biomarkers are changing how we manage acute kidney injury—and its link to chronic kidney disease.

A new study will evaluate the safety and efficacy of universal allogeneic anti-CD19/BCMA CAR T-cells in relapsed or refractory autoimmune diseases including antineutrophil cytoplasmic antibody ...

The kidney is the organ that filters blood and removes excess fluid and waste products, which are excreted in the urine. The kidney also has a role in the regulation of ion concentrations and ...

When harmful bacteria or other microorganisms invade the body, neutrophils, a type of white blood cell, are one of the first immune cells to respond. They release powerful weapons to trap and kill ...

DEAR DR. ROACH: Recently, I almost experienced kidney failure from a probable infection. I am a male, age 68. My glomerular filtration rate (GFR) ranges from 44-50, and my weight is 132 pounds.

Urticarial vasculitis is an autoimmune condition that causes itchy or painful hives. Some people may also develop inflammation in other organs, such as the kidneys or lungs. Vasculitis is a group ...