We show here by single‐molecule methods that a single molecule of SRSF1 can be recruited by a U1 snRNP. This reaction is independent of exon sequences and separate from the U1‐independent process of ...

Background Systemic Lupus Erythematosus (SLE) is an autoimmune systemic disease affecting multiple organs and which is characterized by autoantibodies directed against nuclear constituents. Common ...

Plants have a sophisticated mechanism for monitoring the production of new proteins. The "U1 snRNP" complex ensures that the protein blueprints are fully completed. This is important ...

The U1 snRNP complex is essential in RNA splicing. Now, Peng and his team have demonstrated that the dysfunction of the U1 snRNP contributes to neurodegeneration, opening new avenues of research ...

The yeast U1 snRNP recognizes multiple features of target RNAs to reversibly identify splicing-competent 5' splice sites.

Pretreatment of the U1 snRNP with micrococcal nuclease abolished the assembly of galectin-3 onto this early complex. These data identify galectin-3 as a polypeptide associated with snRNPs in the ...

With Logitech discontinuing its universal remotes, those with multi-device entertainment centers will have to look to alternatives like the SofaBaton U1. This budget option is just $49 — a ...