Researchers have been exploring ways to activate the cGAS/STING pathway in tumors as a way to slow their growth.

The next issue of Top Stories will soon be in your inbox. “Despite robust evidence linking the cGAS-STING pathway to numerous inflammatory and neurodegenerative conditions, the target has historically ...

Sting has confirmed new spring and fall dates in the next U.S. leg of his ongoing Sting 3.0 Tour. Shows kick off with three nights in May at Colorado's picturesque Red Rocks Amphitheater, continue ...

The cGAS-STING signalling pathway has a central role in the innate ... To determine the response of the biosensor to intrinsic sources of dsDNA, we performed apoptosis, TREX1 depletion, DNA ...

Sting has postponed multiple concerts due to a temporary throat infection. On Tuesday, the veteran musician’s team took to social media to announce the postponement, along with rescheduling ...

EXO-TBK1i were also shown to demonstrate enhanced selectivity when compared to a TBK1 active-site, cGAS and STING inhibitors. Additionally, EXO-TBK1is were shown to preserve autophagy, while ...

In a recent interview, Sting discussed Police’s chart-topping hit “Every Breath You Take” from their 1983 album, Synchronicity, and the song’s ties to Sean “Diddy” Combs. During an ...

Nevertheless, Chen showed that cGAMP binds to STING in a manner similar to that of bacterial cyclic dinucleotides to elicit interferon responses, thereby linking DNA sensing by cGAS to STING ...

The Charlotte Sting began play in 1997 and went 15-13 in their inaugural season under head coach Marynell Meadors. Just a couple of years later, they drafted Dawn Staley 9th overall who is now ...

Cyclic GMP-AMP synthase (cGAS) functions as a foreign DNA sensor, triggering an immune response to pathogens by activating the STING (stimulator of interferon genes) receptor. Shortly after its ...