Figure S6. PDE1A promotes the metastatic potential in a cAMP-independent manner. (A) NSCLC cells were transfected with control siRNA and PDE1A siRNA, after 24 h cells were collected for Transwell ...

(A) RCCD1 knockdown efficiency in A549 and PC9 cells measured by qRT-PCR. (B, C) Impact of RCCD1 knockdown on LUAD cell viability assessed by CCK-8 assays. (D, E) Effect of RCCD1 knockdown on colony ...

Fibroblast growth factor receptor 1 (FGFR1) is emerging as a promising molecular target of lung cancer, and various FGFR1 inhibitors have exhibited significant therapeutic effects on lung cancer in ...

Libsyn Podcast PlayerSerial sections of 100 resected GC samples, with PD-L1 expression levels across the dynamic range, were stained with three in vitro diagnostic-grade PD-L1 assays (28-8, 22C3, and ...

The detailed Materials and Methods section is available in the Supplemental Material, including sample collection, 30 RNA-seq, animal model, 31–35 tissue explants, 36 cell culture, 37 cell viability ...

For migration assay, the treated A549 cells (5 × 10 4 cells/well) or HCC1806 cells (8 × 10 5 cells/well) were added to the upper chambers of the non-coated transwell chamber, 8.0 μm (Falcon cell ...

Next, they assessed how AaNRP could act to recruit neutrophils. Firstly, they discounted the ability of AaNRP to be chemotactic through use of transwell assays. Surprising, they also found mast cells, ...