However, far less is known about how stem cells and their progeny maintain normal adult tissue homeostasis in vivo. Recently, we reported studies of cell fate in murine tail epidermis that ...
"We discovered at least two different stem cell populations – one that regenerates tissues such as epidermis and neurons, and another that forms muscles and connective tissue," says Adelmann.
The hair follicle is a major repository for epidermal stem cells. Learning more about the processes that regulate the differentiation of these cells will improve the prospects for skin replacement ...
As a self-renewing organ maintained by multiple distinct stem cell populations, the skin epidermis represents an outstanding, clinically highly relevant research paradigm to address these questions.
"We discovered at least two different stem cell populations—one that regenerates tissues such as epidermis and neurons, and another that forms muscles and connective tissue," says Adelmann.
The body calls on all the stem cells that are in the vicinity of the wound. It doesn’t matter if they’re hair follicle, epidermal, or glandular stem cells. During homeostasis, hair follicle stem cells ...