In April 2025, the FDA granted orphan drug designation to spesolimab-sbzo for the treatment of pyoderma gangrenosum. This ...

Pyoderma gangrenosum is an ulcerating disorder of the skin with sterile neutrophilic inflammation that may be seen in up to 5% of patients with chronic ulceration of the legs. 1 Typically painful, it ...

Ulcerative pyoderma gangrenosum is a rare inflammatory disease with an incidence of 3–10 cases per million per year. 1 Consideration of the diagnosis is based on its classic morphological features: ...

A 35-year-old woman was referred urgently to the dermatology department because of significant wound breakdown 3 weeks following an emergency caesarean section. Examination revealed a full thickness, ...

Source - Mohan AJ, Balakrishnan S, Ambooken B, Ajithkumar K, Asokan N. Superficial variant of pyoderma gangrenosum successfully treated with lower dose clofazimine. Indian Dermatol Online J ...

Pyoderma gangrenosum is an uncommon type of cutaneous ulceration that continues to be a difficult disorder to diagnose and treat 11. It is a neutrophilic dermatosis associated in 70% of the cases with ...

Pyoderma gangrenosum is a rare condition of unknown etiology that was described as an extraintestinal manifestation of inflammatory bowel disease in 1930. At present, there are few well-designed ...

Pyoderma gangrenosum is a rare ulcerative cutaneous disorder commonly associated with systemic diseases such as inflammatory bowel diseases. This paper reports a case of pyoderma gangrenosum affecting ...

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis that manifests as an ulcerative skin disease that uncommonly occurs in patients with FMF. In this case report, we describe a male patient in his ...

Pyoderma gangrenosum is an uncommon type of cutaneous ulceration that continues to be a difficult disorder to diagnose and treat 11. It is a neutrophilic dermatosis associated in 70% of the cases with ...