New research uncovers new insights into preventing chronic inflammation caused by aging-related zombie-like cells. In humans ...
One such mechanism involves a protein called p53. Often dubbed the "guardian of the genome," this protein plays a pivotal ...
Munoz, and Fred Bunz from the Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine studied the tumor-suppressing protein p53, which plays a key role in ...
Munoz, and Fred Bunz from the Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine studied the tumor-suppressing protein p53, which plays a key role in ...
In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and ...
No one really understands why activation of the tumor suppressor p53 sometimes leads to cell-cycle arrest and sometimes induces an apoptotic program. It has been proposed that post-translational ...
New findings show that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress the senescence-associated secretory phenotype (SASP), which causes zombie-like ...
p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells - ...
Shelby is an Assistant Editor for The Scientist. She earned her PhD from West Virginia University in immunology and microbiology and completed an AAAS Mass Media fellowship. View Full Profile. Learn ...