Greatwall, a conserved MAST-like kinase with crucial mitotic entry functions, is curiously absent in worms. Here, the single ...

Protein kinase C (PKC) is as a family of serine/threonine kinases that can be activated by Ca 2+, phospholipid and diacylglycerol. PKC plays an important role in oocyte maturation and activation.

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

Learn how the molecule EBC-46 could advance how HIV is treated and how researchers discovered it.

The table below is a review of notable updates that occurred in January 2025 for investigational products in development.

IDEAYA Biosciences, Inc. (NASDAQ:IDYA – Get Free Report) has earned an average rating of “Moderate Buy” from the sixteen analysts that are covering the firm, Marketbeat.com reports. Two research ...

In cancers, all translocations involving ALK produce fusion proteins with constitutive tyrosine kinase activity that ... Activation of the phospholipase C-γ (PLCγ) pathway is also thought ...

The purpose of this study was to investigate if exertional rhabdomyolysis induced by an acute bout of plyometric exercise in untrained individuals was associated with histological characteristics of ...

ucl.ac.uk Recognising lamin A/C heart disease is important because implantable cardioverter defibrillators need to be implanted early. Promising oral drug therapies are within reach thanks to research ...

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, Aurora, Colorado 80045, ...

Image supplied by WEHI. Calmodulin binds to PSKH1 (in grey) to 'switch on' PSKH1 activity. Reticulocalbin binds to PSKH1 to 'switch off' PSKH1 ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.