Two heads are better than one, as the saying goes, and sometimes two instruments, ingeniously recombined, can accomplish ...
Using the molecules in the spindle of a dividing cell as an example, co-author Rudolf Oldenbourg explained: “With traditional microscopy, including polarized light, you can study the spindle quite ...
A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized ...
The microscope combines polarized fluorescence technology, a valuable tool for measuring the orientation of molecules, with a dual-view light sheet microscope (diSPIM), which excels at imaging ...
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The research is published in Proceedings of the National Academy of Sciences ("Volumetric imaging of the 3D orientation of cellular structures with a polarized fluorescence light-sheet microscope").