This in turn unleashed excitatory neurons to fire more. The authors traced the root cause for all this to a shortage of the synaptic protein neuronal pentraxin 2 (NPTX2) in excitatory neurons.

C-reactive protein (CRP), and pentraxin 3 (PTX3). Our results suggest that charged residues belonging to the apex of the gC1q heterotrimer (with participation of all three chains) as well as the side ...