This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

MANILA – The Philippine Economic Zone Authority (Peza) has approved P52.93 billion worth of investment pledges in the first two months of the year. PEZA reported Tuesday that its investment ...

Figure 8: Regulation of ALDH3A1 and NECTIN4 by p53. Researchers Jessica J. Miciak, Lucy Petrova, Rhythm Sajwan, Aditya Pandya, Mikayla Deckard, Andrew J. Munoz, and Fred Bunz from the Sidney ...

A new research paper was published in Oncotarget, Volume 16, on February 18, 2025, titled "Robust p53 phenotypes and prospective downstream targets in telomerase-immortalized human cells.

One such mechanism involves a protein called p53. Often dubbed the "guardian of the genome," this protein plays a pivotal role in ensuring that your cells grow, divide and die in an orderly fashion.

Studies have found that ROS regulates lipid synthesis and thereby controls colorectal tumorigenesis through a p53-dependent mechanism. In p53 wild-type CRC cells, hydrogen peroxide (H2O2)-induced p53 ...

Gastric cancer remains the fourth most frequently diagnosed malignancy and the fifth leading cause of cancer-related mortality worldwide owning to the lack of efficient drugs and targets for therapy.