This important study suggests that capsaicin nanoparticle administration in rats activates the transcription factor Nrf2 by directly binding to its repressor KEAP1, leading to cytoprotective gene ...
High-throughput screening methods provide efficient measurement of the effects of agents or conditions in biological or chemical assays. These methods often require robotics, imaging and ...
Bioinformatics is a field of study that uses computation to extract knowledge from biological data. It includes the collection, storage, retrieval, manipulation and modelling of data for analysis ...
Circulating kidney injury molecule-1 (KIM-1) in association with kidney injury biomarkers and outcomes in metastatic renal cell carcinoma. This is an ASCO Meeting Abstract from the 2025 ASCO ...
The results also revealed that the nuclear receptor factor 2 (NFE2L2) plays a pivotal role in the signaling of the downstream regulation of oxidative stress pathway genes. Normal human neonatal skin ...
Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, China Department of Molecular, ...
The PPI network indicated NFE2L2, REL, ETV6, MAF, and NF1B as central transcription factors. Conclusion: Based on the bio-informatics analysis of scRNA and high-throughput sequencing data, we ...