Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, ...

Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.

Diabetes, as defined by the World Health Organization, represents a collection of metabolic diseases characterized primarily by hyperglycemia, which can ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

The current state of cardiovascular health globally is significantly influenced by both environmental and metabolic factors, which interplay complexly to ...

Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...

From a study that analyzed brain images of more than 2,500 people with Parkinson's disease in 20 different countries, ...

Objectives To investigate the effect of the L-arginine metabolism on arthritis and inflammation-mediated bone loss. Methods L-arginine was applied to three arthritis models (collagen-induced arthritis ...

When the thyroid isn’t producing enough of certain hormones, metabolism slows down; and when levels of these hormones are too high, metabolism increases. However, this doesn't mean that low levels of ...

Metabolic engineering is the use of genetic engineering to modify the metabolism of an organism. It can involve the optimization of existing biochemical pathways or the introduction of pathway ...

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We see the seven stones of the Molecular Systems Biology cover as a visual allegory for Aristotle's visionary thought: The whole is greater than the sum of its parts.