PRAME expression across many tumor tissues is homogenous. Credit: Nature Medicine (2025). DOI: 10.1038/s41591-025-03650-6 ...

Blueprint Medicines Corporation focuses on Ayvakit, BLU-808, and Elenestinib with strong potential in mast cell disorders. Read why BPMC stock is a strong buy.

The global mast cell tumor treatment market is on a strong growth trajectory, with market projections estimating a valuation of USD 7,836.4 million by 2034. This reflects a steady CAGR of 3.4% from ...

Patients with anaphylaxis or those suspected to have systemic mast cell activation (SMCA) who are initially negative for peripheral blood KIT D816V mutation screening but have high basal serum ...

Mast cell tumors are often involved in allergic reactions and are the most common malignant tumor seen in dogs. They release histamine, which causes irritation and itching, and other chemicals that ...

The biologically aggressive tumor had a low number of mast cells on cytology, consistent with the FC results. A 500-cell differential was performed on a Wright Giemsa stained slide consisting mostly ...

A recent review aimed to characterize the relationship between tumor burden and clinical outcomes in patients treated with chimeric antigen receptor (CAR) T-cell therapy, highlighting the ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists at the German Cancer Research Center (DKFZ) have now shown in mice: mast cells function as a sensor ...

Glioblastoma is a fast-growing and aggressive brain tumor that often kills patients within a year of diagnosis. The cancer starts in the cells called astrocytes, a type of glial or “glue cell ...

Nasal cytology has shown that CRSwNP, generally defined as a Type-2 disease, is characterized not only by eosinophilic but also mast cell inflammation and, in particular, the most severe forms of ...

CAR T cell therapy involves “reprogramming” a person’s own immune cells to fight blood cancers. Currently, approved CAR T cell therapies are designed to attack proteins found in cancer cells.