Review Article Published: 01 May 2002 Evolution of the lectin–complement pathway and its role in innate immunity Teizo Fujita Nature Reviews Immunology 2, 346–353 (2002) Cite this article ...

Dávid Héja, Andrea Kocsis, József Dobó, Katalin Szilágyi, Róbert Szász, Péter Závodszky, Gábor Pál, Péter Gál, Revised mechanism of complement lectin-pathway activation revealing the role of serine ...

In addition to its lectin pathway inhibitors, the company is advancing its development of antibodies and small-molecule inhibitors against MASP-3 to block activation of the alternative pathway.

Narsoplimab is the company’s lead human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2), the effector enzyme of the lectin pathway of the complement ...