After 7 days of culture in OGM, organoids were maintained in OGM or washed with Advanced DMEM/F12 and transitioned to differentiation medium (IntestiCult™ Human Intestinal Organoid Differentiation ...

intestinal organoid cultures and animal models. The researchers found that the ability of rotavirus to generate calcium waves was fully attributable to NSP4, such that expression of NSP4 in cells ...

This marks a significant milestone as SIGX1094 is the first pipeline drug discovered using AI and organoid disease model to enter clinical trials, and the first targeted therapy candidate to ...

The research, published in the journal Gut, used cells donated from 168 patients with Crohn’s disease – a type of inflammatory bowel disease – to generate a biobank of over 300 intestinal epithelial ...

The research team, in collaboration with Professor Hans Clevers, has dedicated seven years to establishing the world's first respiratory organoid culture system using lung adult stem cells and ...

This marks a significant milestone as SIGX1094 is the first pipeline drug discovered using AI and organoid disease model to enter clinical trials, and the first targeted therapy candidate to address ...

Here, we developed an enhanced Caco-2/HT29-MTX-E12 co-culture model incorporating orbital mechanical stimulation to better replicate intestinal conditions and investigate nanoparticle interactions.

A new tablet being developed to cure intestinal worms has shown promising results in trials and could help eradicate the parasitic infection, which affects about 1.5 billion people globally ...

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