It is generally believed that gastric cancer is a multi-step progression from chronic gastritis to gastric atrophy, intestinal metaplasia, dysplasia and cancer. Early gastric cancer is defined as ...
BACKGROUND Biopsy specimens obtained from the gastro-oesophageal junction can reveal intestinal metaplasia in patients presenting for routine upper endoscopy. The site of biopsy may play a critical ...
Intestinal metaplasia is not required for clonal progression. Metaplastic columnar epithelium without goblet cells (‘cardia-type’) and columnar epithelium with goblet cells (‘intestinal metaplasia’) ...