We spatiotemporally pattern these cues using photoinduced degradation, viscoelasticity, and bond formation to study how intestinal stem cell colonies respond to alterations in geometric confinement, ...

The (a) intestine, (b) esophagus and (c) stomach are shown. Quiescent stem cells (d) through asymmetric division probably give rise to more rapidly dividing active stem cells, which then produce ...

Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions ...

Moreover, the 2D structure preserves the natural organization of cells. The top and bottom of a cell remain distinctly separate, as in a real organ. Intestinal cells, for example, have two ...

During this phase, female hormones influence multiple organs to control and change their structure ... the stem cells in the gut via the RANK/RANKL system and then give the intestinal cells ...