We also used gene editing – CRISPR knockout models were generated with EditCo’s XDel technology in combination with our high-throughput gene editing platform. XDel Knockout Cells outperform ...

These tools incorporate a fluorescent reporter for genetic lineage tracing, simultaneously revealing efficient gene knockout in cells marked by the reporter. These strategies hold great potential for ...

Please check back for our new broadcast date. Product safety and efficacy is an integral part of conversations about the potential of cell and gene therapies, particularly when compared to ...

Novel approach to CRISPR editing in immortalized and iPS cell lines offers an efficient, scalable solution for laboratories wanting to streamline and accelerate their research. REDWOOD CITY, ...

However, there could be some common threads that run through all cases. A gene called astrotacton 2 (ASTN2) is one ASD-associated gene that was identified several years ago. Mutations in this gene can ...

Scientists are attempting to tease out those specific associations gene by gene ... Hanzel spent two years creating a knockout mouse that lacked ASTN2, and then studied the brains and activity ...

The pooled format of the fragments enables large-scale high-throughput screening. Twist Multiplexed Gene Fragments (MGFs) Twist Multiplexed Gene Fragments are pools of customizable double-stranded ...

Abstract: The efficient application of the newly developed gene-editing method CRISPR/Cas9 ... to overcome the drawbacks of low efficiency, high toxicity, and cell-type dependency. The high-throughput ...

Fortunately, the advent of high-throughput CRISPR screening has dramatically ... The signal variability caused by different gRNAs targeting the same gene limits the applications of genome-wide ...