aDepartment of Ophthalmology, University Medical Center Utrecht, University Utrecht, the Netherlands bDepartment of Paediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, ...

Uveitis was found in 35.4% overall ... symptoms and also extends what has been reported with both genetic data as well as pertinent clinical information as well as examining specific HLA-B alleles and ...

The relationship of HLA-B27 with axial manifestations and uveitis in pSpA patients is confirmed ... How this study might affect research, practice or policy The knowledge of the potential genetic ...

Patients with late-onset axial spondyloarthritis (axSpA) are less likely to be positive for human leukocyte antigen B27 (HLA-B27 ... different genetic or epigenetic background or rather translates ...

1 HLA genes encode surface marker proteins for leukocyte cells. These genes are closely related and highly polymorphic, meaning they exist in various forms (alleles) in the population. The HLA ...

But that’s probably not the whole story. Many people with AS and anterior uveitis have a gene called HLA-B27. This gene makes eye inflammation much more likely. These symptoms can come on ...

Seronegative spondylitis often occurs with the gene HLA-B27. An estimated 9 in 10 people with ankylosing spondylitis also have the HLA-B27 gene, which usually occurs in only about 7% of the United ...

infective dermatitis and uveitis) [96]. Several studies have found association of the diseases caused by HTLV-I with genes of the HLA system. In a population sample of black Africans infected with ...

For a haplotype to provide maximal information on function, each gene marker is ideally described by a feature that itself has clinical significance. To achieve this, we identified the features of HLA ...

In the study, people carrying a version of the human leukocyte antigen (HLA) gene known as HLA-DRB1*04, or DR4 for short, had 8% to 15% lower odds of developing these neurodegenerative diseases.