Scientists at the McGovern Institute for Brain Research at MIT and the Broad Institute of MIT and Harvard have re-engineered ...

Life is thought to have begun when RNA began replicating itself, and researchers have got close to achieving this in the lab ...

In 2012, scientists Jennifer Doudna and Emmanuelle Charpentier replicated this mechanism found in microbes to develop a ...

The HUGO Gene Nomenclature Committee (HGNC) works under the auspices of Human Genome Organisation (HUGO) and is the only worldwide authority that assigns standardised symbols and names to human genes ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

CRISPR-edited iPSCs uncover early mitochondrial defects shared across ALS mutations, revealing pathways that could guide future treatments.

Researchers characterized pathogens associated with infectious uveitis using conventional diagnostics and metagenomic sequencing in intraocular fluid samples.

N of 1 therapy uniquely developed for infant with life-threatening rare metabolic disorder in six months by Aldevron and ...

But to date this technology -- which allows scientists to use a 'guide' RNA to modify DNA sequences and evaluate the effects -- is able to target, delete, replace, or modify only single gene ...

But to date this technology — which allows scientists to use a “guide” RNA to modify DNA sequences and evaluate the effects — is able to target, delete, replace, or modify only single gene sequences ...

Abstract: CRISPR/Cas9 is a widely used genome editing tool for site-directed modification of deoxyribonucleic acid (DNA) nucleotide sequences. However, how to accurately predict and evaluate the on- ...