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Unexpected solid behavior The researchers focused on studying the behavior of two transcription factors (LHX2, EBF1) and an adapter protein (LDB1). Together, they regulate OR gene expression.
Imaging LHX2 and EBF1 proteins in cultured OSNs. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-59512-9 ...
The following is a summary of “Disruption of the sorcin‒PAX5 protein‒protein interaction induces ferroptosis by promoting the FBXL12-mediated ubiquitination of ALDH1A1 in pancreatic cancer,” published ...
Artificial Intelligence State-of-the-Art AI Predicts Gene Activity in Human Cells AI foundation model may help genetics, cancer, and complex disease research. Posted January 10, 2025 | Reviewed by ...
This NGS-based technology is targeted RNA sequencing, where RNA extracted from the patient sample is reverse transcribed into cDNA, which is PCR amplified to generate enriched libraries that are then ...
A 51-year-old man presented with 1 week of nonproductive cough and dyspnea that limited his ability to climb stairs, previously done with ease. He reported no fever, chest pain, rhinorrhea, or sore ...
Pax5 K198 acetylation regulates gene expression. Credit: Nature Immunology (2024). DOI: 10.1038/s41590-024-01995-7 ...
Reviewer #2 (Public review): Summary: The authors investigate miRNA miR-195 in the context of B-cell development. They demonstrate that ectopic expression of miR-195 in hematopoietic progenitor cells ...
To exclude this possibility, gene expressions of miR-195 transduced Ebf1−/− FL HPCs by cDNA microarray assay were investigated then indicated that miR-195 transduced cells more expressed B cell ...
To assess whether the MoCA score, ARHGAP32, P2RX5, EBF1, and CELSR1 can predict AD dementia in patients with MCI, based on their optimal cut-off value, we divided the patients into the high MoCA score ...
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