Researchers have created a standardized mouse stem cell library containing 63 genetic variants strongly linked to autism ...

Neural organoids and 3D spheroids are a fast-evolving technology with enormous potential for studying brain development and ...

As the global population ages, the risk of developing neurodegenerative diseases such as dementia, Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS) continues to rise.

Now, a new study by University of California San Diego School of Medicine researchers has found that old neurons have unique defects resulting from molecular stress that make them especially ...

Researchers studying nematode worms show that natural sleep and anesthesia both stop movement, but through very different ...

Summary: Scientists have identified a small, specialized group of neurons in the mouse brain that directly influence eating behavior and weight gain. These PNOC/NPY cells, found in the hypothalamus, ...

To test this hypothesis, we created a mouse with conditional knockout of KCC2 in Dlx5-lineage neurons (Dlx5 KCC2 cKO), which targets INs and other post-mitotic GABAergic neurons in the forebrain ...

Neostriatal projection neurons seem to be dynamically and powerfully controlled by GABAergic inputs, but the source(s) and physiological properties of these inputs remain unclear. Here we use ...