From new payload linkers to artificial intelligence partnerships, advances in ADC pipelines push forward selective cancer therapies that minimize side effects.

A woman in Karnataka is the first person identified with the CRIB blood group antigen. Doctors discovered it during a cardiac ...

The debate between CAR T-cell therapy and bispecific antibodies is not a rivalry but a question of sequencing, personalization, and optimization.

Cellular therapies, including chimeric antigen receptor T-cell therapy and bispecific antibodies (BsAbs), have revolutionized the treatment of various B-cell non-Hodgkin lymphomas. A number of agents ...

Though men and women suffer misery-making allergic reactions to countless things, from ragweed pollen to wheat or eggs or the Rh factor from a husband's blood, medical researchers are ...

The effectiveness of surface-immobilized antibodies is often diminished by improper antibody orientation and limited stability, impeding the analytical performance of biosensors. Here, we report a ...

Blood tests for hepatitis A virus IgM, hepatitis B virus core IgM, hepatitis B virus surface antigen, and hepatitis C virus antibodies were all negative.

A chain reaction: HIV vaccines can lead to antibodies against antibodies Date: January 23, 2025 Source: Scripps Research Institute Summary: Many vaccines work by introducing a protein to the body ...

Antibody humanization involves various complex techniques, each designed to reduce non-human antibodies’ immunogenicity while maintaining or improving their therapeutic efficacy.

Patients with rheumatoid arthritis (RA) develop anti-modified protein antibodies (AMPAs), including largely multireactive antibodies against citrullinated, carbamylated, acetylated proteins. Protein ...