Calcium is critical for bone health, optimal muscle activity, and other body processes such as blood clotting and heart function. How much calcium you need depends on your age and stage of life ...

Cancer-associated fibroblasts (CAFs) get a bad rap. The protective, gel-like complex surrounding tumors have been thought to be a no-go for drugs and are known to enforce treatment resistance.

Live calcium imaging was performed by two-photon microscopy using ... on Human Research in full accordance with the declaration of Helsinki principles. Lung fibroblasts isolated were cultured by the ...

Calcium is an essential nutrient needed by all living creatures, including humans. Vitamin D is a prohormone that helps the body absorb calcium, which is essential for bone health. Bones and teeth ...

In the current study we have evaluated the effects of sunitinib and imatinib on both phenotype and function of adult rat CFs to gain insight into possible mechanisms underlying the cardiotoxic ...

The researchers found that in both the mouse model and patient fibroblasts, loss of MICU1 changes the threshold at which mitochondria takes up calcium, meaning the mitochondria cannot sense the ...

In the lab, human cardiac fibroblasts were seen to have the same calcium deposit-forming capabilities. The researchers' best lead against heart calcification is a drug target called ENPP1 ...

Human cardiac fibroblasts were also observed to be capable of forming similar calcium deposits in a laboratory dish. Deb and his team then asked whether heart calcification could be prevented or ...

Abstract: It has been discussed that the increase in the intake ratio of calcium and magnesium (Ca/Mg ratio ... of various ratios of Ca/Mg on the cell viability of cultured fibroblasts at various ...