New research reveals that specialized gut bacteria convert bile acids into powerful healing compounds, offering hope for ...

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism.

Caecal microbiota composition (Illumina Sequencing of the 16S rRNA gene) and key pathways/mediators involved in the control of vascular function, including bile acid (BA) profiling, gut and liver key ...

It has been shown that primary bile acids are capable of inducing cathelicidin gene expression in biliary epithelial cells through the FXR. Secondary bile acids that are byproducts of metabolism ...

Hyaluronic acid is an ingredient that’s talked about a lot, so finding the best hyaluronic acid serum – in which the star ingredient is concentrated – is an essential for plump, juicy and hydrated ...

Intercept Therapeutics’ efforts with FXR agonist Ocaliva (obeticholic acid) ended in disappointment when the US Food and Drug Administration (FDA) rejected the drug for MASH in 2023, forcing the ...

“We are excited to deliver FXR314 and our FXR program to Lilly for Phase 2 and further development. Their world-class development excellence and dedication to delivering for patients will provide an ...

Though heartburn is related to gastroesophageal reflux disease (GERD), the terms are not interchangeable. GERD is a more severe, chronic form of acid reflux, while heartburn is essentially a symptom ...