By modulating these processes, GI exerts downstream regulatory effects that concurrently inhibit multiple cell-death pathways (ferroptosis, pyroptosis, apoptosis, and necroptosis), thereby enhancing ...

In the extrinsic pathway, UV can directly activate Fas cell surface death receptor (Fas), leading to Fas ligand (FasL) binding and the activation of caspase-8 or -10. These initiator caspases then ...