The results presented here give an experimental indication of the associative nature of nucleotidyl transfer performed by DNA ligase on the road to nick repair. Time-resolved solid-state NMR ...

Here we demonstrate a new approach to SNP detection through the application of surface-enhanced Raman scattering (SERS) to the ligase detection reaction (LDR ... We report a limit of detection of 20 ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized ...

A new review sheds light on the complex molecular mechanisms behind Angelman syndrome (AS), a rare neurogenetic disorder, and ...

The Molecular Biology Enzymes, Kits & Reagents Market plays a pivotal role in advancing scientific research and biotechnology development globally. These products form the backbone of molecular ...

A new study in Nature Plants reveals that DNA double-strand break repair (DSBR) pathways help prevent gene transfer from ...

RING E3 ligases act as scaffolds for E2 enzymes ... K63 ubiquitin chains have myriad effects including roles in DNA repair, immunity, endocytosis, and lysosomal degradation. K11 linkages result in ...

before being resuspended in 200 µL 1× ligase (1× T4 ligase buffer, 1:100 dilution of T4 DNA ligase New England Biolabs #M0202S) and incubated at room temperature for 1 h. Following ligation, cells ...

The case went unsolved until it was reopened by Washington County investigators decades later. DNA evidence, in the form of skin cells found on Deborah Atrops’ coat in 2022, led to Robert Atrops ...

The case went cold and remained so until 2023, when advances in DNA and genealogical testing connected the case to a man named Ricky Lee Stallworth. Stallworth was a 27-year-old airman stationed ...