Changes in both DNA alone and the protein–DNA complex provide relevant information about interaction ... (19) Crystallographic data revealed that EndoIII bound to DNA with a covalent intermediate at ...

For many years, the potential of immunoglobulin M (IgM) antibodies was not fully understood because of characteristics different to the well-known immunoglobulin G type like low target affinity, cross ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Chromatin, the mix of DNA and protein that houses each cell's genome, is more resilient to aging than previously thought, suggests a study published in the Journal of the American Chemical Society by ...

EMERYVILLE, Calif., Jan. 28, 2025 (GLOBE NEWSWIRE) -- Totus Medicines, a company revolutionizing small molecule drug discovery and development using covalent DNA-encoded libraries and AI tools ...

The way the body ages could be more resilient than previously thought, a new study suggests.

and Lausanne reveals that the protein machines that shape our DNA can switch directions. The new finding is published in Cell in an article titled, “SMC motor proteins extrude DNA asymmetrically ...

Despite their genius, DNA-nanoparticle motors don't have the speed of their biological counterparts, the motor protein, which is where the issue lies. This is where researchers come in to analyze ...

The problem is that DNA-nanoparticle motors are not as fast as their biological counterparts, the motor protein, despite their genius. Researchers use geometry-based kinetic simulation and ...