Our novel scientific approach focuses on C1q, the initiating molecule of classical complement’s potent inflammatory pathway that when misdirected can lead to tissue damage and loss.

The UCLA team found four distinct progression patterns: Mental health pathway: Psychiatric issues such as anxiety or depression appear early and eventually lead to cognitive decline.

FDA’s Approval of Keytruda for PD-L1 Positive Head and Neck Cancer Patients Signals a Clear Pathway for CEL-SCI’s Multikine to Address a Major Unmet Need in PD-L1 Negative Cancer Patients ...

The classical pathway of SREBP precursor activation refers to transporter cleavage that is dependent on SCAP in response to signals from intracellular sterol depletion.

Crystal precipitation from aqueous solution occurs through multiple pathways. Besides the classical ion -byion addition, non-classical crystallization mechanisms, such as multi-ion polymer and ...

Washington Performing Arts “will not utilize The Kennedy Center” for performances in its upcoming season, the organization announced Thursday. Instead, it says, it will use venues like the Music ...

MaGic trial exceeded enrollment target of 60 patients Top-line results anticipated this September will be the first of three DNTH103 catalysts by YE'26 Building a neuromuscular franchise with DNTH103 ...

In the classical pathway it is activated by antibodies, so it is an antigen driven pathway. In the lectin pathway, carbohydrate epitopes on microbes are recognized.

A new study has shed unprecedented light on the highly variable and climate-sensitive routes that substances from Siberian rivers use to travel across the Arctic Ocean. The findings raise fresh ...

Zaltenibart inhibits the intravascular hemolysis treated by C5 inhibitors as well as the extravascular hemolysis caused by C5 inhibitors in patients suffering from PNH while leaving intact the ...

Zaltenibart, Omeros’ inhibitor of MASP-3, the key activator of the alternative pathway of complement, is advancing toward Phase 3 clinical trials for paroxysmal nocturnal hemoglobinuria and ...

If “invasion” implies chaotic, irregular entry, ending humanitarian parole is more likely to foment it.