The rapid identification of these sequences will permit comparative studies across species, which may uncover key DNA elements and their relationships with rapidly evolving centromere proteins ...

This valuable research advance builds upon previous studies to convincingly show that the centromere-histone core contributes to force transduction through the kinetochore. The centromere mainly ...

Notably, centromere tethering of a Pds5B-binding fragment of ATRX, which lacks the ATPase domain, rescues cohesion defects in ATRX-depleted cells. Furthermore, Wapl depletion bypasses the requirement ...