extracellular matrix they would see in vivo, composed of collagens, proteins and proteoglycans. Migration of some cell types differs dramatically between 2D and 3D worlds (see also Box 1).

In addition to providing a highly organized framework, the ECM mediates signals to and from cells that are involved in important biological processes such as cell differentiation and migration ...

A new study has identified the protein ADAMTS5 as playing a crucial role in the spread of ovarian cancer cells, offering a ...

Espin induces abundant filopodia formation at the leading edge and along the sides, exerting force for cells migrating in ...

and the extent to which the extracellular matrix (ECM) within these gaps is aligned to enable efficient cancer cell migration. "Do the cancer cells move ballistically or diffusively? Can they move ...

Dr. Brüning-Richardson's research is investigating using new drug combinations to prevent or reduce the migration of cancer cells that remain after surgery. The research team hopes to prevent any ...