The panel discussed Project Orbis, ACCESS, and the MAGHP approval pathways, which allow parallel submissions to global agencies. Image credit: GlobalData / Abigail Beaney. Global agencies have ...

Abstract: A nonlinear model reduction method based on time scale analysis was applied to a detailed mechanistic model of the glucose catabolic pathway in S. cerevisiae. The method allows us to ...

Our contribution to this goal is presented herein with the development of a novel palladium-activated prodrug designed to evade the metabolic machinery responsible for 5-FU anabolic activation and ...

Digestion is an example of a catabolic process. In digestion ... For example, amino or fatty acids may be combined to build proteins or lipids through anabolic pathways. Proteins become the building ...

Autophagy, a conserved eukaryotic intracellular catabolic pathway, maintains cell homeostasis by lysosomal degradation of cytosolic material engulfed in double membrane vesicles termed autophagosomes, ...

This work was supported by a Canadian Institutes for Health Research (CIHR) Operating Grant to L.D.E. and graduate scholarship funding from The University of British Columbia and CIHR (to J.M.C.K. and ...

tricornutum. In this review, we outlined the catabolic pathways of all 20 amino acids based on the genome, transcriptome, proteome, and metabolome data. The contribution of these amino acid catabolic ...

In addition, exercise tends to attenuate the activities of the catabolic pathways depicted in Panel A (i.e., the cytokine–NF-κB, glucocorticoid, and activin A–myostatin–SMAD pathways), as ...

We demonstrate this integrative pathway mapping method by predicting the L-gulonate catabolic pathway in Haemophilus influenzae Rd KW20. The prediction was subsequently validated experimentally by ...