Using CRISPR-Cas9, scientists can make precise changes to the genome during brain development, and then closely study how those changes affect individual cells using single-cell transcriptomic ...

A new CRISPR screen method developed at Scripps Research has the potential to improve studies into the genetic underpinnings of human diseases and disorders. The method was outlined in Cell, in a ...

This is a well-written study that presents a solid genetic screen to identify regulators of adipose morphology and remodeling in zebrafish. The authors generated a rigorous screening platform based on ...

"CD Genomics has always been at the forefront of genomics research, and the introduction of our CRISPR Screen Sequencing technology is a significant milestone in our mission to empower researchers ...

Using a new CRISPR-based methodology for modulating DNA structure to enact epigenetic control over specific genes, a team of researchers has identified a “master regulator” gene capable of improving T ...

Researchers from Osaka University developed an in vivo CRISPR screen to analyze factors affecting Toxoplasma gondii fitness in healthy and immunodeficient mice. Mice were infected with Toxoplasma ...

In the study, "Targeting the SHOC2–RAS interaction in RAS-mutant cancers," published in Nature, researchers conducted a genome-wide CRISPR screen to identify genetic dependencies associated with ...