In a ground-breaking first for South Africa and the African continent, local patients are participating in a pioneering international gene-editing clinical trial that may revolutionise treatment for ...

A research team led by Prof. Cao Xiaofeng from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences has uncovered a key translational regulatory mechanism ...

Take a fascinating look back at the science and technology advances that shaped medicine’s past and will define its future.

As a postdoc, Komor found a way to achieve gene-editing with higher efficiencies and a lower incidence of indels by avoiding ...

ACVR2A downregulation disrupts the TCF7/c-JUN pathway, impairing trophoblast invasion and proliferation in pre-eclampsia, revealing a genetic susceptibility-associated mechanism of placental ...

Intellia Therapeutics is a gene editing company focused on the development of Crispr/Cas9-based therapeutics. Intellia's technology platform specializes in Clustered Regularly Interspaced Short ...

These systems — called CRISPR-associated transposases (CASTs) — have been known about since 2017 and act as a way for "jumping genes" to leap around, either within the same cell's DNA or ...

Therefore, using CRISPR-Cas9 technology, they deleted the CD5 gene in CAR T cells, so the engineered cells wouldn't attack each other. This knockout of CD5 in the CAR T cells turned out to provide ...

Ordinary CRISPR-Cas9 gene editing systems cause double-strand ... CRISPR Therapeutics uses a combination of knockout and insertion editing to engineer allogenic chimeric antigen receptor (CAR ...

State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Life Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou ...