This research roundup discusses researchers’ attempts to find a treatment for a “brain fog” that comes with CAR T-Cell ...

In the study, "Targeting the SHOC2–RAS interaction in RAS-mutant cancers," published in Nature, researchers conducted a genome-wide CRISPR screen to identify genetic dependencies associated with ...

05. A strange thing happened weeks before the Food and Drug Administration approved the first treatment made with CRISPR gene editing, an all-but cure for certain patients with sickle cell disease.

Medical anthropologist and bioethicist Julia Brown says scientists and nonscientists need to talk about whether and how we should use CRISPR to edit the fetal genome. When you purchase through ...

Enhancing Immunotherapy and Cancer Research with Advanced CRISPR-Mediated Gene Editing EditCo ... editing portfolio with the launch of Knockout CD8+ T-cell Pools. This new addition builds upon ...

The strategy uses a relatively recent genetic technique called CRISPR, which can make cuts in DNA to introduce errors into viral genetic material within immune cells. “These findings represent a ...

Schematic of the CRISPR/Cas9 system and its nanotechnology delivery methods. The CRISPR/Cas9 system can be delivered in the forms of DNA, mRNA/sgRNA, or ribonucleoprotein (RNP).

Cas9 is directed to its target within the DNA sequence through the use of the guide RNA. A specific sequence of DNA that is between two and five nucleotides in length must align with the 3’ end ...

It’s been a monumental year for Crispr, the molecular tool scientists use to edit genetic material. This November, the United Kingdom authorized the first medical treatment using Crispr gene ...

Vertex Pharmaceuticals plans to sell a gene-editing treatment for sickle-cell disease. A patent on CRISPR could stand in the way. That’s a real nice CRISPR cure you have there. It would be a ...

For validation, the team performed a large-scale CRISPR screen in normal human astrocytes (NHAs) and PDCL SF11411. The CRISPR library encompassed (around 5000) guides targeting non-coding and ...

She became the first sickle-cell patient to be treated with the gene-editing technology CRISPR—and one of the first humans to be treated with CRISPR, period. CRISPR at that point had been hugely ...