Excessive sequestration of KEAP1 into phase-separated p62 bodies under conditions of impaired autophagy drives persistent ...

Lysosomes play a vital role in maintaining cellular health by clearing debris and supporting processes like autophagy. Lysosome impairment contributes to many diseases, including Alzheimer's ...

Enduring a week’s worth of cold water plunges can jolt the body’s cells into starting the process of autophagy to clean up and recycle old, worn-out, and broken parts, according to a new study.

Livre-docente) of the Department of Morphology, Laboratory of Histology and Embryology, Faculty of Dentistry of Araraquara, Universidade Estadual Paulista (Unesp), Araraquara, SP, Brazil Diagram ...

Endogenous interactomes of MFN1 and MFN2 provide novel insights into interorganelle communication and autophagy. Autophagy , 2024; 1 DOI: 10.1080/15548627.2024.2440843 Cite This Page : ...

Get Instant Summarized Text (Gist) Autophagy, particularly through the protein ATG5, plays a crucial role in maintaining brain health by regulating glucose metabolism in neurons. In Purkinje cells ...

Autophagy is a process by which cells break down and recycle their own components to maintain homeostasis. The research team scrutinized the autophagy process in astrocytes and discovered that ...

Autophagy defects have been linked to aging, as well as, with the emergence of age-related disorders, such as diabetes, cardiovascular diseases, cancer and neurodegenerative diseases.

Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons. Nature Aging , 2024; DOI: 10.1038/s43587-023-00548-1 ...

Autophagy is a vital process in which the body’s cells “clean out” any unnecessary or damaged components. It may be possible to induce autophagy, but there may be associated risks ...

Autophagy is a natural, self-preservation mechanism whereby the body removes damaged or dysfunctional parts of a cell and recycles other parts toward cellular repair. Autophagy is the body’s way ...