Watch highlights from Week 18 matchup between the San Francisco 49ers and the Arizona Cardinals during the 2024 NFL season Justin Trudeau says he'll resign as prime minister of Canada Video ...

Relive the San Francisco 49ers 10 best plays from the 2024 NFL Season. Watch the top highlights of San Francisco 49ers wide ...

The Arizona Cardinals and San Francisco 49ers entered the season final both struggling, Arizona having lost five of six and the Niners six of seven. After some early success from the Niners ...

GLENDALE, Ariz. -- Neither the Arizona Cardinals or San Francisco 49ers will be headed to the playoffs this season, but when rivals collide, like these two will at 4:25 p.m. Eastern Sunday on FOX ...

As the 2025 NFL Draft approaches, many mock drafts predict that the San Francisco 49ers will focus on bolstering their offensive line with the 11th overall pick. Mason Johnstone of The Draft ...

The Athletic's Matt Barrows revealed the San Francisco 49ers made a robust offer to Robert Saleh hoping to avoid a lingering coaching search.

Following a narrow 40-34 home loss to the Detroit Lions on "Monday Night Football," the 6-10 49ers conclude the season against the 7-9 Arizona Cardinals on Sunday at State Farm Stadium.

The Arizona Cardinals will host the San Francisco 49ers in a Week 18 battle between two NFC West foes who will wonder where this NFL season went wrong for them. San Francisco (6-10) comes into the ...

Watch highlights from the AFC Championship Game between the Buffalo Bills and the Kansas City Chiefs during the 2024 NFL season. Watch the best plays from Buffalo Bills' running back James Cook's ...

Watch highlights from the AFC Championship Game between the Buffalo Bills and the Kansas City Chiefs during the 2024 NFL season. Watch the best plays from Buffalo Bills' running back James Cook's ...