In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

Antibody makeup influences the severity of flu. Viruses are the fastest-evolving biological entity on earth. This fact ...

Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor for the first time ...

Trials with mice in whom the researchers implanted human glioblastoma cells have already shown that the treatment is very ...

The true function of our endocannabinoid system has been obscured by its name. It has no essential relationship to cannabis ...

A healthy brain balances "activate" and "inhibit" signaling in its neural microcircuitry, with the inhibitory signaling often provided by cell ...

A healthy brain balances “activate” and “inhibit” signaling in its neural microcircuitry, with the inhibitory signaling often provided by cell receptors for the neurotransmitter GABA.   Unexpected ...

T-cell therapy is a revolutionary immunotherapy approach in which T cells are genetically modified to express a receptor that ...

Researchers at the University of Basel have developed CAR T-cells that target glioblastoma, a notoriously aggressive brain ...

T helper (TH) cells are essential immune cells that help other immune cells function effectively. When activated in response to environmental stimuli, these cells can differentiate into either TH1 ...

Researchers have developed an innovative CAR T-cell therapy to combat glioblastoma, the most common malignant brain tumor in ...

Glioblastoma is the most common kind of malignant brain tumor in adults. So far, no treatment has been able to make this ...