GEN - Genetic Engineering and Biotechnology News9d
Holistic Approach to Improving Hard-to-Express Protein Yields
The team was able to reach protein yields at the pool stage that couldn’t be achieved previously with a random integration approach.
The EMBO Journal3d
SERTM2: a neuroactive player in the world of micropeptides
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. In this study, we analyze the long noncoding ...
The EMBO Journal29d
A novel biosensor for the spatiotemporal analysis of STING activation during innate immune responses to dsDNA
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The cGAS-STING signalling pathway has a ...
The Lancet21d
Assessing the oncogenic risk: the long-term safety of autologous chimeric antigen receptor T cells
aCenter for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA bDepartment of Pathology and Laboratory Medicine, University of Pennsylvania ...
Frontiers18d
Advancements in CAR-NK therapy: lessons to be learned from CAR-T therapy
Advancements in chimeric antigen receptor engineered T-cell (CAR-T) therapy have revolutionized treatment for several cancer types over the past decade. Despite this success, obstacles including the ...
Frontiers18d
The Versatile Type V CRISPR Effectors and Their Application Prospects
The class II clustered regularly interspaced short palindromic repeats (CRISPR)–Cas systems, characterized by a single effector protein, can be further subdivided into types II, V, and VI. The ...