Jamie-Lynn Sigler was 20 years old when she learned she had multiple sclerosis, but the last two decades have taught her to ...

Jamie-Lynn Sigler and Robert Iler, who played siblings Meadow and A.J. Soprano, respectively, face off in PEOPLE's exclusive ...

Jamie-Lynn Sigler is reflecting on the scariest time in her life when her 11-year-old son Beau was hospitalized with a life-threatening autoimmune condition last summer. “Those were the hardest ...

Christina Applegate is shedding more light on her battle with multiple sclerosis. “For three years, since I was diagnosed, ...

Jamie-Lynn Sigler’s 10-Year-Old Son Beau Leaves Hospital 33 Days After ‘Nightmare’ Diagnosis Jamie-Lynn Sigler Reveals Son Beau Has Been Diagnosed with Autoimmune Disorder After Catching a ...

Some seven months after her son Beau was hospitalized for 33 days with a rare autoimmune condition, Jamie-Lynn Sigler is now sharing some of the harrowing details of his fight for life.

Christina Applegate and Jamie-Lynn Sigler share painful MS experiences on MesSy podcast, offering support and advice for ...

For three years, since I was diagnosed I’ve been in the hospital upwards of 30 times from throwing up and diarrhea and pain,” ...

"Kelly, I want to address your throwing up and your diarrhea," the Dead to Me actress said on Tuesday's episode of her MeSsy podcast with Jamie-Lynn Sigler. Applegate began to divulge details of ...

The Sopranos' actress Jamie-Lynn Sigler, 43, remembers nights when she ‘fell apart, terrified’ fearing her son Beau 'was going to die' after he was diagnosed with acute disseminated encephalomyelitis, ...

Jamie-Lynn Sigler is going up against her Sopranos brother, Robert Iler, on The $100,000 Pyramid! In PEOPLE's exclusive look at the March 23 episode of the game show, the two former costars ...

Jamie-Lynn Sigler has learned to live with pain since being diagnosed with multiple sclerosis when she was 20 — but nothing prepared her for the kind of anguish she faced last summer when her 11 ...